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Scanning electron microscopy can be divided into thermal electron emission type and field emission type according to the different ways of electron generation. The filament used for thermal electron emission type is mainly tungsten filament electron microscopy. Field emission type The distinction between hot field emission and cold field emission.
In recent years, significant advancements have been made in drug delivery systems using microneedles. Researchers have developed a rocket microneedle drug delivery system that uses a self-propulsion mechanism for deep penetration into the skin and tumor microenvironment. This article discusses the use of rocket microneedles made of mesoporous silica nanoparticles and other materials for the treatment of melanoma, a type of skin cancer.
Bladder cancer, particularly non-muscle invasive bladder cancer (NMIBC), is the most common malignant tumor of the urinary system. Although platinum-based chemotherapy has shown significant clinical efficacy as a first-line treatment, its therapeutic effect is still limited for patients with lymphovascular invasion (LVI). The formation of LVI is closely related to platelets, which not only hinder drug delivery but also protect tumor cells from chemotherapy-induced cell death and immune attack.
A recent study utilizing mesoporous silica nanoparticles (MSN) loaded with trehalose dimycolate (TDM) has shown promise in enhancing the anti-tumor effects of combining the nanoparticles with the WRN nuclease. The research was recently published in Advanced Science on August 29, 2024.
