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Iron oxide nanoparticles are extensively studied for their use in medical applications due to their unique magnetic properties. However, one of the major concerns with the use of inorganic nanoparticles is their potential biotoxicity. Inorganic nanoparticles have a slow clearance kinetics that can pose a potential threat to their in vivo application. The clearance of nanoparticles from the body largely depends on the surface physicochemical properties rather than their size and shape.
Osteoarthritis (OA) is a prevalent disease characterized by subchondral bone fracture, and there is no accurate and specific treatment yet available. Recently, the research team has synthesized a new multifunctional scaffold that can potentially solve this problem. Using photo-polymerized modified hyaluronic acid (GMHA) as a substrate and hollow porous magnetic microspheres (HAp-Fe3O4) as the base, they designed a scaffold with optimum properties for subchondral bone repair.
The accurate diagnosis and treatment of acute ischemic stroke (AIS) require high sensitivity and resolution imaging technologies. Unfortunately, such technologies are still lacking in the field. However, on July 4th, 2024, Small reported the development of a Contrast-Enhanced Susceptibility-Weighted Imaging (CE-SWI) technique that is capable of meeting high-precision imaging needs. The technique employs Fe3O4 nanoparticles modified by Dextran (Fe3O4@Dextran NPs), which allows for high sensitivity and resolution imaging of AIS at 9.4T.
Titanium dioxide is mainly divided into three types: plate titanium dioxide, anatase titanium dioxide, and rutile titanium dioxide. Rutile titanium dioxide and anatase titanium dioxide are two important types of titanium dioxide, which are currently the most widely used in the market. However, their properties differ greatly.
The combination of flexibility and elasticity makes elastic materials essential in a wide range of industries, including automotive, construction, and consumer goods. Moreover, they are increasingly attractive in emerging fields such as microfluidics, soft robotics, wearables, and medical devices. However, having sufficient mechanical strength is a prerequisite for any application. Thus, solving the seemingly contradictory attributes between softness and strength has always been an eternal pursuit.
