In recent years, significant advancements have been made in drug delivery systems using microneedles. Researchers have developed a rocket microneedle drug delivery system that uses a self-propulsion mechanism for deep penetration into the skin and tumor microenvironment. This article discusses the use of rocket microneedles made of mesoporous silica nanoparticles and other materials for the treatment of melanoma, a type of skin cancer.
Bladder cancer, particularly non-muscle invasive bladder cancer (NMIBC), is the most common malignant tumor of the urinary system. Although platinum-based chemotherapy has shown significant clinical efficacy as a first-line treatment, its therapeutic effect is still limited for patients with lymphovascular invasion (LVI). The formation of LVI is closely related to platelets, which not only hinder drug delivery but also protect tumor cells from chemotherapy-induced cell death and immune attack.
A recent study utilizing mesoporous silica nanoparticles (MSN) loaded with trehalose dimycolate (TDM) has shown promise in enhancing the anti-tumor effects of combining the nanoparticles with the WRN nuclease. The research was recently published in Advanced Science on August 29, 2024.
As 3D printing technology continues to advance, the demand for high-quality printing materials has never been greater. One such material is TC4 alloy powder, which has a wide range of applications in aerospace, engineering, and medical industries. One of the main challenges when it comes to printing with TC4 alloy powder is creating a consistent and high-quality powder that can be used in the printing process. In this article, we will explore the different methods for preparing TC4 alloy powder for 3D printing.
Nano boron carbide and ultrafine boron carbide powder were prepared by variable current laser ion vapor phase method. Boron carbide, also known as black diamond, has a molecular formula of B4C and is usually a gray black micro powder. It is one of the three hardest materials known (the other two being diamond and cubic boron nitride). Hard black glossy crystal. The hardness is lower than industrial diamond, but higher than silicon carbide. Compared to most pottery, it has lower fragility. Has a large thermal neutron capture cross-section. Strong chemical resistance. Not susceptible to corrosion by hydrogen fluoride and nitric acid. Dissolved in molten alkali but insoluble in water and acid.
