Recent breakthrough research published in the journal Small in April 2025 has unveiled a groundbreaking approach in cancer treatment. Scientists have developed a multifunctional nano-delivery system, TMBFG, by surface modifying MXene powder through a non-chemical modification strategy using bovine serum albumin (BSA). This innovative system combines MXene with manganese dioxide (MnO2) nanoparticles, folic acid (FA), and glucose oxidase (GOx) to target cancer cells, induce starvation, and achieve photothermal double killing effects.
Boron nitride has excellent properties such as high temperature resistance, oxidation resistance, chemical corrosion resistance, and neutron absorption, and has low dielectric constant and dielectric loss.
Powder metallurgy is an important part of the new material field, playing a crucial role in promoting the transformation and upgrading of China's manufacturing industry. With its unique process advantages, powder metallurgy technology enables material performance optimization, meeting the diverse needs of different customers in various complex conditions.
In recent years, significant advancements have been made in drug delivery systems using microneedles. Researchers have developed a rocket microneedle drug delivery system that uses a self-propulsion mechanism for deep penetration into the skin and tumor microenvironment. This article discusses the use of rocket microneedles made of mesoporous silica nanoparticles and other materials for the treatment of melanoma, a type of skin cancer.
Bladder cancer, particularly non-muscle invasive bladder cancer (NMIBC), is the most common malignant tumor of the urinary system. Although platinum-based chemotherapy has shown significant clinical efficacy as a first-line treatment, its therapeutic effect is still limited for patients with lymphovascular invasion (LVI). The formation of LVI is closely related to platelets, which not only hinder drug delivery but also protect tumor cells from chemotherapy-induced cell death and immune attack.
A recent study utilizing mesoporous silica nanoparticles (MSN) loaded with trehalose dimycolate (TDM) has shown promise in enhancing the anti-tumor effects of combining the nanoparticles with the WRN nuclease. The research was recently published in Advanced Science on August 29, 2024.
